2012 Annual Meeting: Primary Immune Deficiency Diseases North American Conference, May 17-20, 2012, Chicago, IL

AARDA Satellite: Sex, Gender, & Autoimmunity Through the Lifespan
Thursday, May 17
8:00am - 4:30pm

Registration

Pre-registration has closed. On-site registration will be available to those interested in attending the AARDA Satellite. The AARDA Satellite is an additional fee and is not included with registration to the Annual Meeting.

AARDA Satellite

$150 ($100 if also attending Annual Meeting)

Annual Meeting Registration Fees

CIS Members	$300
Non-Members (MD, PhD, DO	$450
CIS Trainee Members	$100
Non-Member Trainee	$150
Allied Health (MS, MSN, MA, PA)	$125
Developing Country Member/Non-Member	$150

Program Outline - Thursday, May 17

7:00am - 8:00am	Breakfast
8:00am - 8:05am	Welcome
8:05am - 9:50am	Session 1: Hormones and Autoimmunity Chair: Betty Diamond, MD, Head, The Center for Autoimmune and Musculoskeletal Disease The Feinstein Institute for Medical Research North Shore - LIJ Health System 8:05am - 8:35am IRF4 and its regulators: potential molecular targets for sex hormones in autoimmunity Alessandra Pernis, MD, Senior Scientist, Hospital for Special Surgery 8:35am - 9:05am Sex hormones in autoimmunity: emerging roles for the interferon-inducible p200-family proteins Divaker Choubey, PhD, Professor, Department of Environmental Health, University of Cincinnati College of Medicine 9:05am - 9:50am Estrogen Affects on Autoantibody Production Betty Diamond, MD
9:35am - 9:50am	Break
9:50am - 11:50am	Session 2: Chromosomes and Autoimmunity Chair: Bruce Richardson, MD, PhD, Professor of Internal Medicine, Chief, Section of Rheumatology, Ann Arbor Veteran Affairs Hospital, University of Michigan Medical School 9:50am - 10:20am X-linked Gene Dosage and Autoimmunity: Too Little or Too Much Pietro Invernizzi, MD, PhD, Head, Hepatobiliary Immunopathology Unit, Department of Internal Medicine, IRCCS Instituto Clinico Humanitas, University of Milan 10:20am - 10:50am Sex Chromosomes in Autoimmune Disease Rhonda Voskuhl, MD, Neuroimmunology, Neuroendocrinology, and Neuroprotection, Ronald Reagan UCLA Medical Center 10:50am - 11:20am Chromosomes and autoimmunity: The FMR1 gene Norbert Gleicher, MD, Medical Director, Center for Human Reproduction 11:20am - 11:50am Genetics, Epigenetics, Gender and Lupus Bruce Richardson, MD, PhD, Professor of Internal Medicine, Chief, Section of Rheumatology, Ann Arbor Veteran Affairs Hospital, University of Michigan Medical School
11:50am - 12:50pm	Lunch
12:50pm - 2:20pm	Session 3: Immunology of Pregnancy Chair: Noel R. Rose, MD, PhD, Professor of Pathology, Professor of Molecular Microbiology and Immunology, Director, Johns Hopkins Center for Autoimmune Disease Research, Bloomberg School of Public Health 12:50pm - 1:20pm Autoimmune Hypophysitis Patrizio Caturegli, MD, Associate Professor, Johns Hopkins Bloomberg School of Public Health 1:20pm - 1:50pm Maternal Anti-Ro Antibodies and Fetal Susceptibility Link Inflammation to Fibrosis in Passively Acquired Cardiac Manifestations of Neonatal Lupus Jill P. Buyon, MD, Professor; Departments of Hospital for Joint Diseases and Medicine (Rheum Div) 1:50pm - 2:20pm Immunology of Pregnancy Daniel A. Kahn, MD, PhD, Assistant Professor, Dept of OB/GYN, Davis Geffen School of Medicine UCLA
2:20pm - 2:35pm	Break
2:35pm - 4:30pm	Session 4: Environmental Influences Chair: Lisa G. Rider, MD, Deputy Chief Environmental Autoimmunity Group NIEHS, NIH 2:35pm - 3:05pm Epidemiology of Autoimmune Disease Risk: Sex, Development, and Time Windows for Exposure Karen Costenbader, MD, Associate Professor of Medicine, Brigham and Womens Hospital 3:05pm - 3:35pm Understanding the role of the environmental factors in development of autoimmunity: why sex matters Christine Parks, M.S.P.H., PhD, Epidemiology Branch, National Institute of Environmental Sciences 3:35pm - 4:04pm Sex ration in MS - a surrogate for incident - possible mechanisms George Ebers, MD, Department of Clinical Neurology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
4:05pm - 4:30pm	Question and Answer Session

Program Goal

The goal of this program is to address the role of gender in autoimmune disease. Sessions will focus on the predisposition to autoimmune disease in women, delineating the influence of hormones and chromosomes. Environmental influences that are mediated through sex hormones or have a differential impact based on gender will be addressed. The immunology of pregnancy, the effect of menarche, pregnancy, menopause on autoimmune disease will be addressed, including the controversial area of microchimerism. Speakers' presentations will include molecular mechanisms and clinical implications.

Program Target Audience

This program is intended to provide a broad overview of the field for both investigators and clinicians.

Program Objectives

To discuss the science behind the female predisposition to autoimmune disease.
To distinguish hormonal from sex-determined gender differences.
To understand environmental triggers and their gender biased impact.
To understand clinical implications of the science.

Attendees will learn

hormonal and sex-determined influences on the immune system.
incidence and severity of autoimmune disease through the lifespan
influences of pregnancy on autoimmune disease.

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