Meetings

2004 Spring School in Systemic Autoimmune Diseases


Thursday, March 18, 2004
8:00pm-10:00pm Reception/Introduction
9:15pm-9:30pm Introductory presentation
George Tsokos, MD
Friday, March 19, 2004
7:30am-8:00am Breakfast
8:00am-10:00am Case presentations by students
(20 min + 10 discussion)
SLE Basic
8:00am-8:30am Case 1
Phenotypic and Functional Analysis of EBV-specific Memory CD8 Cells in SLE
Beate Berner, MD, PhD
8:30am-9:00am Case 2
CREM suppresses the expression of c-fos and the activity of AP-1 in SLE T cells
Vasileios Kyttaris, MD
9:00am-9:30am Case 3
Regulatory T Cells in Systemic Lupus Erythematosus
José C. Crispin, MD
9:30am-10:00am Case 4
Study Of Cell Death By Human Monoclonal Autoantibody Probes
Roopali Gandhi, MD
10:00am-10:30am Break
10:30am-12:00pm Faculty Presentations
(35 presentation + 10 discussion)
SLE Basic
10:30am-11:15am Faculty 1
Systemic Lupus Erythematosus: From Pathogenesis to Rational Treatment
George Tsokos, MD
11:15am-12:00pm Faculty 2
Genetic Basics of Kidney Disease
Robert Kimberly, MD
12:00pm-1:30pm Group Lunch/Informal Discussions
1:30pm-3:30pm Case presentations by students
(20 min + 10 discussion)
SLE Clinical
1:30pm-2:00pm Case 1
Antiphospholipid Antibodies as a Cause of Diffuse Alveolar Hemorrhage
Kevin Deane, MD
2:00pm-2:30pm Case 2
Lymphedema in JRA
Beata A. Puri, MD
2:30pm-3:00pm Case 3
A Case of Psychosis in a 9 Year Old Girl With SLE
Abigail Smukler, MD
3:00pm-3:30pm Case 4
Microchimerism in Systemic Lupus Erythematosus
Christine B. Bernal, MD
3:30pm-4:00pm Break
4:00pm-5:30pm Faculty Presentations
(35 presentation + 10 discussion)
SLE Clinical
4:00pm-4:45pm Faculty 1
Promising Therapies for Systemic Lupus Erythematosus
Vibeke Strand, MD
4:45pm-5:30pm Faculty 2
Tissue Damage in Systemic Lupus Erythematosus & Sjorgen's Syndrome-A Role of Adhesion Modules
Tsutomu Takeuchi, MD
8:00pm Group Dinner/Social
Saturday, March 20, 2004
8:00am-10:00am Case presentations by students
(20 min + 10 discussion)
Inflammation
8:00am-8:30am Case 1
Ajulemic Acid, A Nonpsychoactive Cannabinoid, Modulates Activation of Fibroblast-like Synovial Cells
Judith Stebulis, MD
8:30am-9:00am Case 2
Pediatric Uveitis
Stacy Ardoin, MD
9:00am-9:30am Case 3
Treatment of Seronegative Spondyloarthropathy with Anti-TNF Biologic Response Modifiers: A VA Collaborative Cohort
Anthony Turkiewicz, MD
9:30am-10:00am Case 4
Some Thoughts on Psoriatic Arthritis
Dimitris Daoussis, MD
10:00am-10:30am Break
10:30am-12:00pm Faculty Presentations
(35 presentation + 10 discussion)
Inflammation
10:30am-11:15am Faculty 1
Stress Proteins and the Immune Response: Not a One Way Street
Gabriel Panayi, ScD, MD
11:15am-12:00pm Faculty 2
Molecular and Cellular Basis of Rheumatoid Joint Destruction and Gene Transfer to Detect Novel Targets for the Treatment of Rheumatoid Arthritis
Steffen Gay, MD
12:00pm-1:30pm Group Lunch/Informal Discussions
1:30pm-3:30pm Case presentations by students
(20 min + 10 discussion)
Inflammation 2
1:30pm-2:00pm Case 1
Platelet TGF-B1 Compartmentalization and Activation
Nathalie Burg, MD
2:00pm-2:30pm Case 2
Corticotropin Releasing Hormone as a Candidate Gene in Rheumatoid Arthritis
Sophia Steer, MD
2:30pm-3:00pm Case 3
Disturbed Peripheral B cell Homeostasis in Human Immunodeficiency and Autoimmunity
Klaus Warnatz, MD
3:00pm-3:30pm Case 4
B cell Activating Factor Belonging to the Tumor Necrosis Factor Family (BAFF) Synthesis Regulation in Peripheral Blood Mononuclear Cells: Search for a New Therapeutic Target for BAFF Related Autoimmune Diseases
Katsuya Suzuki, MD
3:30pm-4:00pm Break
4:00pm-5:30pm Faculty Presentations
(35 presentation + 10 discussion)
Inflammation 2
4:00pm-4:45pm Faculty 1
Rheumatologic Complications of Chronic Renal Failure
Jonathan Kay, MD
4:45pm-5:30pm Faculty 2
What Have We Learned From Randomized Controlled Trials in RA?
Vibeke Strand, MD
Free Evening No organized social event
Sunday, March 21, 2004
8:00am-10:00am Case presentations by students
(20 min + 10 discussion)
Inflammation/Autoimmunity
8:00am-8:30am Case 1
A Case of Recurrent Fever, Sinus Tachycardia Hypotension
Richard Chou, MD, PhD
8:30am-9:00am Case 2
A 56 Year Old Man with Polyglandular Autoimmune Disease and Chronic Urticaria
Mary Klote, MD
9:00am-9:30am Case 3
Predictors of Carotid Athersclerosis in SLE: One Step Toward CVD Prevention
Kathleen Maksimowicz-McKinnon, MD
9:30am-10:00am Case 4
Autoimmune Mechanisms in Atherosclerosis: The Role of Heat-shock Protein 60
Michael Hans Knoflach, MD
10:00am-10:30am Break
10:30am-12:00pm Faculty Presentations
(35 presentation + 10 discussion)
Inflamation/Autoimmunity
10:30am-11:15am Faculty 1
Clinical Target Setting in the Management of Rheumatoid Arthritis: The Time is Now
Gabriel Panayi, ScD, MD
11:15am-12:00pm Faculty 2
Diversity in Host Defence: Functional Genomics of Fc Receptors
Robert Kimberly, MD
12:00pm-1:30pm Group Lunch/Informal Discussions
1:30pm-3:30pm Case presentations by students
(20 min + 10 discussion)
Inflamamation/Autoimmunity 2
1:30pm-2:00pm Case 1
Autologous Joint Tissue for Suppression of Rheumatoid Arthritis: A Novel Approach to Oral Tolerance
Todd Funkhouser, MD, PhD
2:00pm-2:30pm Case 2
"Increased FcgRI Expression in IFN-g Primed Human Macrophages Enhances TNF-a Production after Fcg Receptor (FcgR) Crosslinking"
Petros Efthimiou, MD
2:30pm-3:00pm Case 3
Macrophages Enhances TNF-a Production after Fcg Receptor (FcgR)
Andrew Zeft, MD
3:00pm-3:30pm Case 4
Sjorgren's Syndrome, MALT Lymphoma and Cryoglobulinemeia
Iulia Grillo, MD
3:30pm-4:00pm Case 5 IVIG and Thromboembolic Events Associated with Therapy Bonnie Bidinger, MD
4:00pm-4:30pm Break
4:30pm-6:00pm Faculty Presentations
(35 presentation + 10 discussion)
Inflammation/Autoimmnity 2
4:30pm-5:15pm Faculty 1
Targeted Therapy for Scleroderma
Virginia Steen, MD
5:15pm-6:00pm Faculty 2
Environmental and Genetic Aspects of Autoimmune Diseases: The Case for Elemental Disorders
Frederick Miller MD, PhD
7:00pm-9:00pm Social Event-Dinner/Adjourn

Key Participants

Invited Faculty:

Chairman:
George C. Tsokos, MD
Vice Chair of Research Programs
Uniformed Services University
Bethesda, MD

Steffen Gay, MD
Director
WHO Collaborating Center for Molecular Biology &
Novel Therapeutic Strategies for Rheumatic Diseases
University Hospital Zurich
Zurich, Switzerland

Jonathan Kay, MD
Clinical Director
Rheumatology Unit
Massachusetts General Hospital
Boston, MA

Robert P. Kimberly, MD
Professor of Medicine
University Alabama-Birmingham
Birmingham, AL

Frederick Miller, MD PhD
Chief, Environmental Autoimmunity Grp
NIH, National Inst. Of Environmental Health Sci.
Bethesda, MD

Gabriel S Panayi, ScD, MD, FRCP
Arthritis Research Campaign Professor of Rheumatology
Guy's, King's and St Thomas' School of Medicine
King's College London, Guy's Hospital
London, United Kingdom

Vibeke Strand, MD
Clinical Professor, Division of Immunology
Stanford University
Stanford, CA

Applicants:

Dr. Stacy Ardoin, MD
Duke University Medical Center
Durham, NC

Dr. Chistine Bernal, MD
Baylor College of Medicine
Houston, TX

Dr. Beate Berner, MD, PhD
Case Western Reserve University
Cleveland, OH

Dr. Bonnie Bidinger, MD
University of Massachusettes Medical School
Worcester, MA

Dr. Nathalie Burg, MD
The Rockefeller University
New York, NY

Dr. Richard Chou MD, PhD
Harvard University School of Medicine
Boston, MA

Dr. Iulia Circiumaru Grillo, MD
Roger Williams Medical Center
Providence, RI

Dr. Jose Carlos Crispin Acuna, MD
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Mexico City, Mexico

Dr. Dimitrios Daoussis, MD
University of Patras School of Medicine
Patras, Greece

Dr. Kevin Deane, MD
University of Colorado Health Sciences Center
Denver, CO

Dr. Petros Efthimiou, MD
Hospital for Special Surgery, Weill Medical College Cornell University
New York, NY

Dr. Todd Funkhouser MD, PhD
Walter Reed Army Medical Center
Silver Spring, MD

Dr. Roopali Gandhi, MD
National Institute of Immunology Varinder Nagar
New Delhi, India

Dr. Mary Klote, MD
Walter Reed Army Medical Center
McLean, VA

Dr. Michael Hans Knoflach, MD
University of Innsbruck, Medical School
Innsbruck, Austria

Dr. Vasileios Kyttaris, MD
Washinton Hospital Center
Washington, DC

Dr. Kathleen Maksimowicz-McKinnon, MD
The Cleveland Clinic Foundation
Cleveland, OH

Dr. Abigail Smukler, MD
University of Michigan
Ann Arbor, MI

Dr. Judith Stebulis, MD
University of Massachusettes Medical School
Worcester, MA

Dr. Sophia Steer, MD
Guy's, King's and St. Thomas' School of Medicine
London, UK

Dr. Katsuya Suzuki, MD
Saitama Medical Center/Saitama Medical School Chuo-ku
Tokyo, Japan

Dr. Anothony Michael Turkiewicz, MD
Georgetown University Medical School
Arlington, VA

Dr. Nancy Walker, MD
University of Massachusettes Medical School
Worcester, MA

Dr. Klaus Warnatz, MD
University Clinic, Albert-Ludwigs University of Freiburg
Freiburg, Germany

Dr. Andrew Zeft, MD
University of Washington
Seattle, WA